PFE Unusual Options Activity

As of Oct 20, 2026, our scanner has flagged 200 unusual PFE options trades in its recent history: 160 bullish and 40 bearish, totaling $504.8M in premium. Flow has leaned leaned bullish (call buying), with $457.2M in bullish call premium vs. $47.5M in bearish put premium. The most recent PFE trade was flagged at 13:00 ET on Oct 20, 2026.

200Flagged trades

160Bullish

40Bearish

$504.8MTotal premium

$3.1MLargest trade

Recent PFE options flow

13:00 ET
Oct 20, 2026
29762 $PFE Oct 23rd 2026 30 PUTS BOUGHT@ 0.3 vs Open Interest of 190 for a total of $791669. 156.6x volume/OI ratio.
BEARISH
09:30 ET
Sep 9, 2026
66749 $PFE Sep 18th 2026 28 PUTS BOUGHT@ 0.5 vs Open Interest of 32574 for a total of $3073791. 2x volume/OI ratio.
BEARISH
10:15 ET
Sep 1, 2026
43168 $PFE Sep 18th 2026 28 PUTS BOUGHT@ 0.3 vs Open Interest of 12132 for a total of $1286406. 3.6x volume/OI ratio.
BEARISH
09:30 ET
Jul 24, 2026
15044 $PFE Jul 31st 2026 24 CALLS BOUGHT@ 1 vs Open Interest of 1213 for a total of $1517488. 12.4x volume/OI ratio.
BULLISH
15:45 ET
Jul 23, 2026
15039 $PFE Jul 31st 2026 24 CALLS BOUGHT@ 1 vs Open Interest of 2342 for a total of $1516984. 6.4x volume/OI ratio.
BULLISH
09:30 ET
Jun 26, 2026
30194 $PFE Jul 17th 2026 24.5 PUTS BOUGHT@ 0.7 vs Open Interest of 8255 for a total of $2054702. 3.7x volume/OI ratio.
BEARISH
12:18 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
12:05 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
11:49 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
11:33 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
11:17 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
11:03 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
10:48 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
10:35 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
10:18 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
10:06 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
09:49 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
09:34 ET
Jun 8, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
15:48 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
15:35 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
15:18 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
15:02 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
14:48 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
14:35 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
14:20 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
14:03 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
13:48 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
13:33 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
13:02 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
12:49 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
12:33 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
12:19 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
12:03 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
11:48 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
11:35 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
11:19 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
11:04 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
10:49 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
10:21 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
10:04 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
09:49 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
09:35 ET
Jun 5, 2026
2716 $PFE Jun 18th 2026 30 PUTS BOUGHT@ 4.1 vs Open Interest of 905 for a total of $1120350. 3x volume/OI ratio.
BEARISH
12:34 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:18 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:03 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:50 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:33 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:21 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:04 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
10:47 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
10:32 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
10:20 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
10:04 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
09:47 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
09:33 ET
May 29, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
15:47 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
15:33 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
15:17 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
15:02 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
14:48 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
14:32 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
14:18 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
14:03 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
13:49 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
13:33 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
13:16 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
13:03 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:47 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:32 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:19 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:01 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:47 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:32 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:18 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:03 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
10:48 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
10:31 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
10:18 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
10:03 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
09:49 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
09:32 ET
May 28, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
15:48 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
15:33 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
15:18 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
15:02 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
14:33 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
14:18 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
14:02 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
13:48 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
13:32 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
13:19 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
13:03 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:49 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:31 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:18 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
12:03 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:48 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:34 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:19 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH
11:03 ET
May 27, 2026
3421 $PFE Jun 18th 2026 18 CALLS BOUGHT@ 8.4 vs Open Interest of 235 for a total of $2874564. 14.6x volume/OI ratio.
BULLISH

How to read PFE unusual options activity

Each row is a single PFE options trade where same-day volume was large relative to open interest and the premium was large. Bullish means calls were bought at or above the ask; bearish means puts were bought at or above the ask. Volume above open interest suggests, but does not prove, that new positions were opened. Check whether PFE open interest rose the next day to confirm. Learn more in our guide to unusual options activity and volume vs. open interest.

PFE options flow FAQ

Is there unusual options activity in PFE today?

Our most recent flagged PFE trade was at 13:00 ET on Oct 20, 2026. This page lists every recent PFE trade our scanner flagged, newest first, and refreshes every few minutes during market hours.

Is PFE options flow bullish or bearish right now?

Of 200 recent flagged PFE trades, 160 were bullish (calls bought at or above the ask) and 40 were bearish (puts bought at or above the ask). Large put buying is often hedging, so treat this as positioning data, not a prediction.